Chronic renal failure : note
• Chronic renal failure may develop in patients with poorly controlled diabetes mellitus.
• Chronic renal failure is
characterized by heavy
proteinuria,
nausea, tiredness, weakness and abnormal concentrations of creatinine, electrolytes and urea (uraemia) in blood.
There may also be symptoms of headache and neurological changes.
• Loss of albumin in the urine following glomerular
dysfunction causes
oedema, which is often first seen in the
dependent parts of the body, for example ankles.
• Renal failure cause increase in potassium (K+) blood level which leads to muscle weakness and may cause cardiac rhythm disturbance; and decrease in calcium (Ca2+) blood levels which leads to defective mineralization of bones (osteomalacia).
• Renal failure may cause anaemia because of deficient renal secretion
of erythropoietin. Erythropoietin stimulates production of red cells
in bone marrow.
- Prepared by: Dr. Mohamed Abdel Rahman (pharmacist).
- Resources: - Clinical physiology and pharmacology,Farideh Javid and Janice McCurrie 2008.
- Copyrights: All rights are reserved for pharmacist development group 2009 - 2011.
|
Posted by Unknown
on 2/10/2011.
Filed under
diseases,
notes,
urinary tract
.
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